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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0466f4aa351853adacb97159da2052dae45e21f76432c73e71caed6456e5c6bf' 
  AND token = 'vNVPWGkqoO/Hw6tf0102/Sh7aZXwTF+8gNxDw9rzwv8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}