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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c594b1e0c3c425f217cc2620c3db271eb9f13f2954d0bd32d61598b28cb2fa63' 
  AND token = 'r03urCAhUT6/PYJlrV5fBMK8OW2VUNgfwkkmHYH0ejs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}