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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '224a11ba919ed77def77600e03a6450d57178317fb489968f2c20e21d88c4ca5' 
  AND token = 'uRa1KqnfGlBKrwhvztNKH61pL5F96nbn7oCUiJ6dveU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}