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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '83a77e9d2c2fe312278ddc84e01441274d0e6dc3b75584fc722422390b5bf844' 
  AND token = 'N8ctCVda/+qo/v22OHP/u22LIqFyRmd0ZLHDS7UD12E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}