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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06308187032a4227412f805cce63e4c3222f06154a0f3fd50d21b9c4449da3e2' 
  AND token = 'e16N5L+zwc05fG3DndXFLZuVeTAZWHysjBBsY2Dws+0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}