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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d53a1c9e9821879121c267e70275825dbe8952da50856d74928693e871fcbb3' 
  AND token = '21Tfh2ftmNSlIr8BCm3PFIHn3icXiC3FH2OqGEFNS+Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}