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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5fd35fb072a4d03aa6e1494670f510c1a9c6af055219ca84e0016627032848f5' 
  AND token = 'y2VhGGqeCGHkbuUUOln8uvWq8HWmOdNj8lfIaQZtb1I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}