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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8d9dd4c0fda4b764c23aa2f7a194a67ec11b634066f953bbd9f9dede426e644' 
  AND token = 'BOOvbuW56ghjm91Gx6xrGjM8mbmiC2x73eMLf965D0c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}