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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '146bd63942d705e7fd60abe5f766212ecbaeedf270f1e52a5ff98cb6e20f4665' 
  AND token = 'IVLjAGf58ywvEoXDUcpmS3kVXqLx2E83MsBPh8vJLrg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}