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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '881a5a6e34d645aa3eeaf6d072e3fc0d4707e3488f6984c8518a3d8662579509' 
  AND token = '1rZHsErCJeNOpXu38RsM+dIZW3LZU3PicZKldgV7834=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}