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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0fa76dbf18f9262b4e56f9f0fb11c79f44f7722b829f116be046a57decbea960' 
  AND token = 'GvyQUMR91pfgv/hEJrmstGH2nlrpU/TetFHBi+SZyg8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}