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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cdbdf0137c8d9159277d34cb7a0c3d862abd1d1d0e54c39f78356a2c437a2bb2' 
  AND token = 'd7TmpIPDHZ1ueY4IMEANTr1oshkDynn9UjY9kicocyg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}