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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e55a42ecb25b3f37eb722947ba7a23a2e2c729ba01841fca750872f9ac9729f2' 
  AND token = 'b+/NAwlkI1w0oybt56HmH5XJOAWs+UuHVFXBvstmmeQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}