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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57d0778421813e0f2fb309fd445cd1e0686d8f9bd80d5e15711f7cf8797d8c75' 
  AND token = 'QVJtIGtyqpQCpv3jHyY7K4dt7dKLGakLQ+KRY5ZI5sM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}