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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78b316794dab8ad5e83418dd2b2e71aa9cbfab75cad5186d69bc70bddebbde6a' 
  AND token = 'iUs9iPSO8EskXqLB8jnIns+Ip18qvg7ME0RYLoXW5Rw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}