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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c1ab345189b015c2266c0569f5344b39cce8b5686dedf01d28a71f3879d5f0a' 
  AND token = 'c5q3BHoilJ/fOJc53y2K4hYWteviSshkMxlfbhGvt/s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}