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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0a06d1d40226fbc2afcb77026c19d294c0477b0b5a753e19b359cb761059a2d' 
  AND token = 'fTqIJSZrAY+Zxa7yipMzg/tvejWzxSQ7zjTlRat2P5Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}