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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64e7d7aa4f2388a8a17a0f4816fa29de87a9c73417cab1d5330324c87111994c' 
  AND token = '5CVdQBaKJZRox//XLsIh10m9jXrMiQtFsg0dL68KIyc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00066

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}