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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de22ae0b5f08d47cc0a51cbd4fe5d4bd66ec7ed405b2e992ca57e1544c070211' 
  AND token = 'TP9q0nUdyCB5M2zfXhMsyP7Jd30DwbQLWh738VuaI2M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}