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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '496015ed4dbd1262650acecba11bdfe5afdd16672b8e50fc80f7559b457923c5' 
  AND token = 'RCoRiZY9BSuJjSybXwpLguZCfv7MdZ4eWxdx/pFxhJ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}