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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb887dea679d0cb100622622d0e5f0eccb48beca2dfde8bf55f72c6ec1da80b5' 
  AND token = 'xIMq4qCZeWlGoR4LcEXeLFBncKCe6QBwGaNax2OY9OI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}