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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '169d4f2d9171a2b43fdc0dfb16949bbfaf0f9d7988224a2abaf6a753706a4f16' 
  AND token = '+U+wP4CnFIX39W79pWIUJ6Ev4q124qWlhQQC35ZCTSA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}