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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f9d7d95925b444827e77854ef9a5cc369bfa3d22e8a176ddb0d826ed8d25f1d' 
  AND token = 'dx116sqi3pgyaz2atlzRRpVKLcWwewRmeWQGqhdv2UY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}