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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6434b57175a0e6475876f6dbde4e7be14638017c9e4d6be66dcb6175c32f014a' 
  AND token = 'iu3qrrqR6eob74t+SjcryuPWO8wBG50ni8rcOV5Sx7Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}