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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10405c1ec569b9f83ceb8d2aec0219f720c0ad1f49e72f1f4124b02f6f101f27' 
  AND token = 'VpwYRIgI9egvn62YPaREJF+HjSjywZ30Sss38lkHtU0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}