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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a428b71614caf2340f79cd190fd59a683a4dbba2bc9251058d539fa2ae5b6446' 
  AND token = '036S4PcQKe+QfhblCPbDzj59P6w+TqL0l7v6Q5VOJ6Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}