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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '215e81035003eb4722e305a142245516a3e4bae4f8283fc79e2e69d0aa270d2e' 
  AND token = 'A/66+FlXk8arZRe4IWlSMhB4h1YdZst3bu+G9Rv7/cI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}