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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9ce30c3fde82ce9b3f59a265dbb85774c16eaf1ff8264dfd726a034fdd2c38d' 
  AND token = 'LoMbyVcaB77qXZjxdPwwV+CLkmIqqEkjMyFMZCC4Dfc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}