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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '025b46b6497da5cc0ff48594d981309a3996bb30be8f2618f8452c988b6343a3' 
  AND token = 'FCosWFv++YUq9YUkVMeQsh06n2tGYyWrHVH2EYMCRa0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}