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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9390641c70cf60a860356cd56a3a5074e894fab3ad9e07b1d64f96d49c1f06d9' 
  AND token = 'ye3E4HgzKbsWXkjt5r/CyMmKMvTGIcmLTUFBHjI09VQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}