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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4a6eb5e3d601eebff74a784f29f2eb0d4d8fd8d536b7a7b8198b365530a216d' 
  AND token = 'sfuCLnC5b58K8jW6ocM76LZimvAEcKPtGmTwgqHKmT0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}