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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1540c9aa617ac3a1fe6101c7c39f7070e5719fa21603f9beb9846fbefdfbeba9' 
  AND token = '2cmhdhqtlsuHLxtAHyQMXUYL4TUpRJAlPa0vyKhRb24=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}