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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44721171769c2258fc0656c62c2fc2a1dcec62a0be719737bb3522269cbc0648' 
  AND token = 'CNh1gBxMsobB9i6EQcR3IUKPGIH2aQ7kpt3HciQ6x/4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}