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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd158be54bb35b2644e4c9eefd02e2db723d1137a0819976f496620dbe98c12b0' 
  AND token = 'qdEOfqhWL4l9x8TLTVbuPgSp9e2jDs/+VL0hylcNEEg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}