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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d6ae185262848bced77012a01044bd3674879c4474c9cfd7ae7a7c1f809273e' 
  AND token = 'gfFglTf8OfFAhkBUa9NdlR8he2EosKxm/cf/OqtePyg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}