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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d01e6bdd3975bea856fcaedcd307438fc7e636c3d42f0da83f9af4ad1c65a99' 
  AND token = 'SwahSm1zSm7ZSDfj5FvEghhkmHF3KWTUAS0cpDo+FSY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}