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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0388890c11a65a656ba47805d45998a7dbecb9807d97f3e9c10547126796f85' 
  AND token = '18O4xaMTsAFVLmWrSPMpiP2xQ8G5IJr+w/D2BrKig/k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}