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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ffe692913a342589e694ad198a98e12e642f3f8f0b24b7f0a63a540b4991633' 
  AND token = 'nghbtOUordyLli/NJV2RqaNANLSh0xtz1L8iWjt9cjM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}