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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '505ecb19fc0fdc61b8ed3d035d35bdd34cecf33e16558349c7c16a3eedf10ce2' 
  AND token = 'lpGhHv3XxkeHAbTLUqqUAZAWogoLX+eq0dlJEXMBafo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00063

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}