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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa4b221d638e5f3ad9b627943d3b68dca07cb028d6e50840302830fe023fa3f5' 
  AND token = 'X8jGbf4NoUDTq3JS7mNZaySWgGDMsbDpQ/D8n/XxWVw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}