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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b40100b38c4a87097f1712612f3abb2e36681e27b9524754bc6d4a67c3376244' 
  AND token = 'LF6NpD7cS0v0oVi6AtwQnttXeS+qHk4N5txuBXAUodg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}