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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e723f777b073e96302d68a964c1261653aec53cf8481e352659f8d744c7cd40' 
  AND token = 'COSnfOqnDYI/NsS8f8rVjfg35IwWQZr606oPm4yuNlM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}