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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33f4658b324de3b71c489d7d3f2d388201a0df078b96c3117966d66f9ac24054' 
  AND token = 'ogKFFWiZr0DfRc55D4KBnsoMez8GePu4T8RGxVK0cSg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}