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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a94b078cc5de719de4abfb5e1354697cfe9f29615aa21ee392aec77ce70f718f' 
  AND token = 'V19HK7Kwj+SM359idTs5rG1gixCmvoXZCZwbJdWPxPg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}