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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b05eb430c1346a6e3e1f512a782a8d02d1492e2618857d34ff6e2613919f6322' 
  AND token = 'HK4qdO8/NIE6yFYoM1kwijx9Q1MEQdmGe1f3CwYvYvI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}