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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '76826290b4e79e27b4b689d31cc9c831a724c00a07c2b6f082794bdf911bb304' 
  AND token = '8Z6hP55uW03ZsUHb/WRx2IRV4Fd+aBeiypzxJ3+7E3w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}