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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dfcf21abccade070c3cfcc036246db9389181465830f92b1f23e1fe6e1a7cb95' 
  AND token = 'Dt9xJfuAJcypisLpAq2gwKn2TIYzb2iCH4lf+tUquwc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}