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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '71878ff09f5980020c1fb20b47ae2a690cf004b622f60c5674e5df9b497ac928' 
  AND token = 'Im5aqlfe75My/0gd5q5/pGCzus+CCTWApHYrpZn3scQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}