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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66c47dc526d74e080edbeeacefba94c3cb31cf5b07922cb800cea992dca97251' 
  AND token = 'CNtBknmNsIGJ5Qr2c4eJzWIhpA8HeVAZsEltDtRRvm0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}