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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29e81da1377096454753d75b15b551bbeb7d197ff074e6c696396a7c6c00baff' 
  AND token = '0IPwXFGJETzyuCl3pWavuBEA+7537L5DQuBfI2GyhvQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}